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To detect naturally occurring antioxidative components from unused marine resources, the screening test for the antioxidants containing in starfish, ascidian skin, cuttlefish ink, echinoid skin, Sargassum harneri, Agarum cribrosum, Odonthalia corymbifera and Desmarestia ligulata was carried out. The ether, acetone and methanol fractions successively extracted from Odonthalia corymbifera were very effective on prevention of the nonenzymatic lipid oxidation and their IC_(50), (a concentration to inhibit 50% of control lipid oxidation rate) were 30, 100 and 200 μg/mL, respectively. The water and methanol extracts obtained from cuttlefish ink also revealed strong antioxidant effect and their IC_(50), were 390, 100 μg/mL, respectively.
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